(5-Methyl-1,2-oxazol-3-yl)methanol → 8-(3,5-Bis-trifluoromethyl-benzoyl)-3-(5-methyl-isoxazol-3-yl-methyl)-1-o-tolyl-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Reaction equation
[CH3:36][c:37]1[cH:38][c:39]([CH2:42][OH:43])[n:40][o:41]1.[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][C:11]3([C:12](=[O:24])[NH:13][C:14](=[O:23])[N:15]3[c:16]3[c:17]([CH3:22])[cH:18][cH:19][cH:20][cH:21]3)[CH2:25][CH2:26]2)[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1)([F:34])[F:35]>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][C:11]3([C:12](=[O:24])[N:13]([CH2:42][c:39]4[cH:38][c:37]([CH3:36])[o:41][n:40]4)[C:14](=[O:23])[N:15]3[c:16]3[c:17]([CH3:22])[cH:18][cH:19][cH:20][cH:21]3)[CH2:25][CH2:26]2)[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1)([F:34])[F:35]Participants
3
Sources & evidence
- ORD record
- ord-a8d76ad815db46c38d07287b08abfd85
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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