2-Propenoic acid, 3-(3-methoxyphenyl)- → N-[1-[[5-(1,1-difluoroethyl)furan-2-yl]methyl]pyrazol-3-yl]-3-(3-methoxyphenyl)prop-2-enamide

HRID 933180Notes

Reaction equation

HRID 933180 reaction equation
[CH3:17][O:18][c:19]1[cH:20][c:21]([CH:25]=[CH:26][C:27](=[O:28])[OH:29])[cH:22][cH:23][cH:24]1.[F:1][C:2]([CH3:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:10][n:11]2[n:12][c:13]([NH2:16])[cH:14][cH:15]2)[o:9]1>>[F:1][C:2]([CH3:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:10][n:11]2[n:12][c:13]([NH:16][C:27]([CH:26]=[CH:25][c:21]3[cH:20][c:19]([O:18][CH3:17])[cH:24][cH:23][cH:22]3)=[O:28])[cH:14][cH:15]2)[o:9]1

Participants

3

Reactant 2

HCID 871552-Propenoic acid, 3-(3-methoxyphenyl)-HCID 669293691-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine

Product 1

HCID 66928293N-[1-[[5-(1,1-difluoroethyl)furan-2-yl]methyl]pyrazol-3-yl]-3-(3-methoxyphenyl)prop-2-enamide

Sources & evidence

ORD record
ord-59af29d5e7f3443eb2de0039560d1596
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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