Acetate → Ethyl 4-hydroxy-5-methylquinoline-3-carboxylate

HRID 933208Notes

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]([CH3:18])[c:6]2[c:7](=[O:17])[c:8]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[cH:9][nH:10][c:11]12.[CH3:20][C:21](=[O:22])[O-:23].[Na+:19]>>[cH:2]1[cH:3][cH:4][c:5]([CH3:18])[c:6]2[c:7](=[O:17])[c:8]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[cH:9][nH:10][c:11]12

Participants

Reactant 3

HCID 175Acetate

HCID 923Sodium ion

HCID 59410078ethyl 8-bromo-5-methyl-4-oxo-1H-quinoline-3-carboxylate

Product 1

HCID 21829729Ethyl 4-hydroxy-5-methylquinoline-3-carboxylate

Sources & evidence

ORD record: ord-7002722b23f84aefa6b107859b639ac4
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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