4-Bromo-2-(trifluoromethoxy)iodobenzene → 7-(4-Bromo-2-trifluoromethoxy-phenyl)-1-ethyl-4,4,6-trimethyl-3,4-dihydro-1H-quinolin-2-one
Reaction equation
[Br:26][c:27]1[cH:28][c:29]([O:34][C:35]([F:36])([F:37])[F:38])[c:30]([I:33])[cH:31][cH:32]1.[CH2:1]([CH3:2])[N:3]1[C:4](=[O:25])[CH2:5][C:6]([CH3:23])([CH3:24])[c:7]2[cH:8][c:9]([CH3:22])[c:10]([B:13]3[O:14][C:15]([CH3:16])([CH3:17])[C:18]([CH3:19])([CH3:20])[O:21]3)[cH:11][c:12]21>>[CH2:1]([CH3:2])[N:3]1[C:4](=[O:25])[CH2:5][C:6]([CH3:23])([CH3:24])[c:7]2[cH:8][c:9]([CH3:22])[c:10](-[c:30]3[c:29]([O:34][C:35]([F:36])([F:37])[F:38])[cH:28][c:27]([Br:26])[cH:32][cH:31]3)[cH:11][c:12]21Participants
3
Sources & evidence
- ORD record
- ord-11955ae315a9416a8a91cfb5650f543e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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