2-Methoxy-5-(trifluoromethoxy)benzaldehyde → 1-(2-Methoxy-5-trifluoromethoxy-phenyl)-3-phenyl-prop-2-yn-1-ol

HRID 933384Notes

Reaction equation

HRID 933384 reaction equation
[CH3:20][O:21][c:22]1[cH:23][cH:24][c:25]([O:30][C:31]([F:32])([F:33])[F:34])[cH:26][c:27]1[CH:28]=[O:29].[F:1][c:2]1[cH:3][cH:4][c:5]([O:18][CH3:19])[c:6]([CH:8]([C:9]#[C:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[OH:17])[cH:7]1>>[c:2]1([O:30][C:31]([F:32])([F:33])[F:34])[cH:3][cH:4][c:5]([O:18][CH3:19])[c:6]([CH:8]([C:9]#[C:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[OH:17])[cH:7]1

Participants

3

Reactant 2

HCID 27833642-Methoxy-5-(trifluoromethoxy)benzaldehydeHCID 670676721-(5-Fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol

Product 1

HCID 670676931-(2-Methoxy-5-trifluoromethoxy-phenyl)-3-phenyl-prop-2-yn-1-ol

Sources & evidence

ORD record
ord-050172bc2ba641e9adf1933b663ff368
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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