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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 933495Generated: October 30, 2026

Palladium → 3-tert-butoxycarbonyl-7-chloro-6-{5-[2-(cyclopropylmethyl-amino)-thiazol-4-yl]-pyridin-2-ylthiomethyl}-2,3,4,5-tetrahydro-1H-benzo[d]azepine

https://huagongshe.com/reaction/933495

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPalladiumHCID 23938—
Reactant1,4-DioxaneHCID 31275—
ReactantDiisopropylethylamineHCID 81531—
ReactantDibenzylidene acetoneHCID 95417—
ReactantHCID 59822270HCID 59822270—
Reactant3-tert-Butoxycarbonyl-7-chloro-6-mercaptomethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 59822276—
Product3-tert-butoxycarbonyl-7-chloro-6-{5-[2-(cyclopropylmethyl-amino)-thiazol-4-yl]-pyridin-2-ylthiomethyl}-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 86623711—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d9fc8f1c16dc49b29281087c3a027b9d
Source noteValidation data from https://doi.org/10.1039/C8SC04228D