4-Methylbicyclo[2.2.2]octan-1-amine → 4-Fluoro-1-[2-[(4-methyl-1-bicyclo[2.2.2]octanyl)amino]acetyl]pyrrolidine-2-carbonitrile
Reaction equation
[Br:11][CH2:12][C:13](=[O:14])[N:15]1[CH:16]([C:21]#[N:22])[CH2:17][CH:18]([F:20])[CH2:19]1.[NH2:1][C:2]12[CH2:3][CH2:4][C:5]([CH3:10])([CH2:6][CH2:7]1)[CH2:8][CH2:9]2>>[NH:1]([C:2]12[CH2:3][CH2:4][C:5]([CH3:10])([CH2:6][CH2:7]1)[CH2:8][CH2:9]2)[CH2:12][C:13](=[O:14])[N:15]1[CH:16]([C:21]#[N:22])[CH2:17][CH:18]([F:20])[CH2:19]1Participants
3
Sources & evidence
- ORD record
- ord-674c0b2086b94d2497d3ca990af4e97c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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