1-(3,5-Dichlorophenyl)piperazine → 3-{4-[4-(3,5-dichlorophenyl)-piperazine-1-yl]-butyl}-3-ethyl-5-fluoro-1,3-dihydro-2H-indol-2-one
Reaction equation
[Cl:19][c:20]1[cH:21][c:22]([N:27]2[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]2)[cH:23][c:24]([Cl:26])[cH:25]1.[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1([CH2:17][CH3:18])[C:7](=[O:16])[NH:8][c:9]2[cH:10][cH:11][c:12]([F:15])[cH:13][c:14]21>>[CH2:2]([CH2:3][CH2:4][CH2:5][C:6]1([CH2:17][CH3:18])[C:7](=[O:16])[NH:8][c:9]2[cH:10][cH:11][c:12]([F:15])[cH:13][c:14]21)[N:30]1[CH2:29][CH2:28][N:27]([c:22]2[cH:21][c:20]([Cl:19])[cH:25][c:24]([Cl:26])[cH:23]2)[CH2:32][CH2:31]1Participants
3
Sources & evidence
- ORD record
- ord-14f8f0ffeeac4e5db34b1c39c6bd17a5
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…