Water → 1-[6-(Trifluoromethyl)pyridin-3-yl]ethan-1-one
Reaction equation
[CH3:17][NH:18][N:19]([C:20]([CH3:21])=[O:22])[NH:23][CH3:24].[CH3:26][CH2:27][O:28][CH2:29][CH3:30].[CH:12]([Li:13])([CH2:14][CH3:15])[CH3:16].[F:1][C:2]([c:3]1[n:4][cH:5][c:6]([Br:9])[cH:7][cH:8]1)([F:10])[F:11].[OH2:25]>>[F:1][C:2]([c:3]1[n:4][cH:5][c:6]([C:20]([CH3:21])=[O:22])[cH:7][cH:8]1)([F:10])[F:11]Participants
6
Sources & evidence
- ORD record
- ord-41a5433df86346f58890a9f833ac8118
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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