Dimethylamine → 4-dimethylaminomethyl-6-(3-fluoro-4-methylphenyl)-2-isobutyl-2H-pyridazin-3-one
Reaction equation
[CH3:26][NH:27][CH3:28].[F:1][c:2]1[cH:3][c:4](-[c:9]2[cH:10][c:11]([CH2:20][O:21][S:22]([CH3:23])(=[O:24])=[O:25])[c:12](=[O:19])[n:13]([CH2:15][CH:16]([CH3:17])[CH3:18])[n:14]2)[cH:5][cH:6][c:7]1[CH3:8].[OH2:29]>>[F:1][c:2]1[cH:3][c:4](-[c:9]2[cH:10][c:11]([CH2:20][N:27]([CH3:26])[CH3:28])[c:12](=[O:19])[n:13]([CH2:15][CH:16]([CH3:17])[CH3:18])[n:14]2)[cH:5][cH:6][c:7]1[CH3:8]Participants
4
Sources & evidence
- ORD record
- ord-e3f07e65b27d4c6b8767fb49b059ad7b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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