Chloroform → 8-fluoro-2,3,4,4a,5,10b-hexahydro-1H-benzo[h]isoquinolin-6-one
Reaction equation
[CH:21]([Cl:22])([Cl:23])[Cl:24].[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:17]1)[C:7](=[O:16])[CH2:8][CH:9]1[CH2:10][CH2:11][N:12]([CH3:15])[CH2:13][CH:14]21.[N:18]#[C:19][Br:20]>>[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:17]1)[C:7](=[O:16])[CH2:8][CH:9]1[CH2:10][CH2:11][NH:12][CH2:13][CH:14]21Participants
4
Sources & evidence
- ORD record
- ord-41a6929532f64052980f2d61fb09278d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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