Methyl 5-amino-2-fluorobenzoate → 5-{[5-(2-adamantan-1-yl-ethyl)-2-(2,4,6-trimethyl-pyridine-3-yl)-1H-imidazole-4-carbonyl]-amino}-2-fluoro-benzoic acid methyl ester
Reaction equation
[C:1]12([CH2:11][CH2:12][c:13]3[c:14]([C:27](=[O:28])[OH:29])[n:15][c:16](-[c:18]4[c:19]([CH3:26])[n:20][c:21]([CH3:25])[cH:22][c:23]4[CH3:24])[nH:17]3)[CH2:2][CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2.[CH3:30][O:31][C:32]([c:33]1[c:34]([F:40])[cH:35][cH:36][c:37]([NH2:39])[cH:38]1)=[O:41]>>[C:1]12([CH2:11][CH2:12][c:13]3[c:14]([C:27](=[O:28])[NH:39][c:37]4[cH:36][cH:35][c:34]([F:40])[c:33]([C:32]([O:31][CH3:30])=[O:41])[cH:38]4)[n:15][c:16](-[c:18]4[c:19]([CH3:26])[n:20][c:21]([CH3:25])[cH:22][c:23]4[CH3:24])[nH:17]3)[CH2:2][CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-21bbd380ad6340fd9af9ea31c7e25ce1
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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