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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 934240Generated: October 31, 2026

Hydrochloric Acid → 7-{5-Chloro-4-[2-(1-methyl-1H-imidazol-2-yl)-phenylamino]-pyrimidin-2-ylamino}-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one

https://huagongshe.com/reaction/934240

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant2-MethoxyethanolHCID 8019—
Reactant1,4-DioxaneHCID 31275—
Reactant7-Amino-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-oneHCID 57853830—
Reactant(2,5-Dichloro-pyrimidin-4-yl)-[2-(1-methyl-1H-imidazol-2-yl)-phenyl]-amineHCID 86633891—
Product7-{5-Chloro-4-[2-(1-methyl-1H-imidazol-2-yl)-phenylamino]-pyrimidin-2-ylamino}-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-oneHCID 51031002—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-f9503139221146f8a6673b95d2a99848
Source noteValidation data from https://doi.org/10.1039/C8SC04228D