Acetate → [7-(2-Chloro-5-methoxy-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(4-methyl-piperazine-1-sulfonyl)-phenyl]-amine

HRID 934370Notes

Reaction equation

HRID 934370 reaction equation
[Br:22][c:23]1[cH:24][cH:25][c:26]([S:29](=[O:30])(=[O:31])[N:32]2[CH2:33][CH2:34][N:35]([CH3:38])[CH2:36][CH2:37]2)[cH:27][cH:28]1.[C:51]([O-:52])(=[O:53])[CH3:54].[C:56]([O-:57])(=[O:58])[CH3:59].[CH3:39][C:40]([CH3:41])([O-:42])[CH3:43].[Cl:1][c:2]1[c:3](-[c:10]2[cH:11][c:12]3[c:13]([n:14][c:15]([NH2:18])[n:16][n:17]3)[c:19]([CH3:21])[cH:20]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[K+:44].[O:45]1[CH2:46][CH2:47][O:48][CH2:49][CH2:50]1.[Pd+2:55]>>[Cl:1][c:2]1[c:3](-[c:10]2[cH:11][c:12]3[c:13]([n:14][c:15]([NH:18][c:23]4[cH:24][cH:25][c:26]([S:29](=[O:30])(=[O:31])[N:32]5[CH2:33][CH2:34][N:35]([CH3:38])[CH2:36][CH2:37]5)[cH:27][cH:28]4)[n:16][n:17]3)[c:19]([CH3:21])[cH:20]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 813Potassium CationHCID 312751,4-DioxaneHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 7107291-(4-Bromophenylsulfonyl)-4-methylpiperazineHCID 45749132-Methylpropan-2-olateHCID 248227537-(2-Chloro-5-methoxyphenyl)-5-methylbenzo[e][1,2,4]triazin-3-amine

Product 1

HCID 59837790[7-(2-Chloro-5-methoxy-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(4-methyl-piperazine-1-sulfonyl)-phenyl]-amine

Sources & evidence

ORD record
ord-0e056344b92849e08c9509c885761683
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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