Toluene → (2-Chloropyridin-3-yl)methanol

HRID 934504Notes

Reaction equation

HRID 934504 reaction equation
[CH2:2]([Al+:3][CH2:4][CH:5]([CH3:6])[CH3:7])[CH:8]([CH3:9])[CH3:10].[CH2:30]([Cl:31])[Cl:32].[CH3:11][c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1.[Cl:18][c:19]1[c:20]([C:21](=[O:22])[O:23][CH2:24][CH3:25])[cH:26][cH:27][cH:28][n:29]1.[H-:1]>>[Cl:18][c:19]1[c:20]([CH2:21][OH:22])[cH:26][cH:27][cH:28][n:29]1

Participants

6

Reactant 5

HCID 1140TolueneHCID 6344DichloromethaneHCID 166653HydrideHCID 2796614Ethyl chloronicotinateHCID 16686348Bis(2-methylpropyl)alumanylium

Product 1

HCID 2763647(2-Chloropyridin-3-yl)methanol

Sources & evidence

ORD record
ord-784b678a401b4be1a818c69530baced5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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