3-hydroxy-3-[2-hydroxy-5-(trifluoromethyl)phenyl]-1-pentyl-1,3-dihydro-2H-indol-2-one → 3-[2-hydroxy-5-(trifluoromethyl)phenyl]-1-pentyl-1,3-dihydro-2H-indol-2-one
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([OH:6])[c:7]([C:8]2([OH:9])[c:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[N:16]([CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[C:22]2=[O:23])[cH:24]1.[OH:25][C:26]1([c:41]2[c:42]([OH:51])[cH:43][cH:44][c:45]([C:47]([F:48])([F:49])[F:50])[cH:46]2)[C:27](=[O:40])[N:28]([CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])[c:29]2[cH:30][cH:31][cH:32][cH:33][c:34]21>>[CH:26]1([c:41]2[c:42]([OH:51])[cH:43][cH:44][c:45]([C:47]([F:48])([F:49])[F:50])[cH:46]2)[C:27](=[O:40])[N:28]([CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])[c:29]2[cH:30][cH:31][cH:32][cH:33][c:34]21Participants
3
Sources & evidence
- ORD record
- ord-9cb065045e7b40b28574f4b30e7d1887
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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