Cyclobutanecarbonyl chloride → 1-Cyclobutylcarbonylamino-2-(2-hydroxymethylphenyl)ethane
Reaction equation
[CH:12]1([C:16](=[O:17])[Cl:18])[CH2:13][CH2:14][CH2:15]1.[NH2:1][CH2:2][CH2:3][c:4]1[c:5]([CH2:10][OH:11])[cH:6][cH:7][cH:8][cH:9]1.[c:19]1([C:20]2=[N:30][CH2:29][CH2:28][c:22]3[c:21]2[cH:27][cH:26][cH:25][c:23]3[Cl:24])[cH:31][cH:32][cH:33][cH:34][cH:35]1>>[NH:1]([CH2:2][CH2:3][c:4]1[c:5]([CH2:10][OH:11])[cH:6][cH:7][cH:8][cH:9]1)[C:16]([CH:12]1[CH2:13][CH2:14][CH2:15]1)=[O:17]Participants
4
Sources & evidence
- ORD record
- ord-9b1ce04ffbcc4d39b373ace50f517981
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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