2-Chloro-5-fluorophenol → tert-butyl 4-[1-[[5-chloro-2-(2-chloro-5-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoate
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:26])[cH:6][c:7]1[C:8](=[O:9])[NH:10][CH:11]([CH3:12])[c:13]1[cH:14][cH:15][c:16]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[cH:24][cH:25]1.[Cl:27][c:28]1[c:29]([OH:35])[cH:30][c:31]([F:34])[cH:32][cH:33]1>>[c:2]1([O:35][c:29]2[c:28]([Cl:27])[cH:33][cH:32][c:31]([F:34])[cH:30]2)[n:3][cH:4][c:5]([Cl:26])[cH:6][c:7]1[C:8](=[O:9])[NH:10][CH:11]([CH3:12])[c:13]1[cH:14][cH:15][c:16]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[cH:24][cH:25]1Participants
3
Sources & evidence
- ORD record
- ord-35d337bdbb7443f4a029886243b8bf9b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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