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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 934740Generated: October 30, 2026

Tetrahydrofuran → Methyl 2-[2-methyl-4-[3-[4-(3-morpholin-4-ylprop-1-ynyl)phenyl]-3-[3-(trifluoromethyl)phenyl]prop-2-enoxy]phenoxy]acetate

https://huagongshe.com/reaction/934740

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladiumHCID 23938—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant4-(2-Propyn-1-yl)morpholineHCID 412941—
ReactantMethyl 2-[4-[3-(4-iodophenyl)-3-[3-(trifluoromethyl)phenyl]prop-2-enoxy]-2-methylphenoxy]acetateHCID 90997013—
ProductMethyl 2-[2-methyl-4-[3-[4-(3-morpholin-4-ylprop-1-ynyl)phenyl]-3-[3-(trifluoromethyl)phenyl]prop-2-enoxy]phenoxy]acetateHCID 90819474—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-b26771adc8b9414d82fb992d98045845
Source noteValidation data from https://doi.org/10.1039/C8SC04228D