Acetate → 5-[3-Chloro-4-(cyano-dimethyl-methyl)-phenyl]-3-cyclopentyl-3-hydroxy-pent-4-enoic acid
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([Cl:13])[c:5]([C:8]([C:9]#[N:10])([CH3:11])[CH3:12])[cH:6][cH:7]1.[C:27]([O-:28])(=[O:29])[CH3:30].[CH3:34][CH2:35][OH:36].[CH:14]1([C:19]([CH2:20][C:21](=[O:22])[OH:23])([CH:24]=[CH2:25])[OH:26])[CH2:15][CH2:16][CH2:17][CH2:18]1.[H:32][H:33].[Na+:31].[O-:38][C:39]([CH3:40])=[O:41].[O-:42][C:43]([CH3:44])=[O:45].[OH-:46].[OH-:47].[Pd+2:37].[Pd+2:48]>>[c:2]1([CH:25]=[CH:24][C:19]([CH:14]2[CH2:15][CH2:16][CH2:17][CH2:18]2)([CH2:20][C:21](=[O:22])[OH:23])[OH:26])[cH:3][c:4]([Cl:13])[c:5]([C:8]([C:9]#[N:10])([CH3:11])[CH3:12])[cH:6][cH:7]1Participants
9
Reactant 8
HCID 175Acetate3×
HCID 702Ethanol
HCID 923Sodium ion
HCID 961Hydroxide2×
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)2×
HCID 468356463-Cyclopentyl-3-hydroxypent-4-enoic acid
HCID 587626012-(4-Bromo-2-chlorophenyl)-2-methylpropanenitrile
HCID 178418361HCID 178418361, compoundProduct 1
Sources & evidence
- ORD record
- ord-26efa422a1574d80b4348cf088a5edc2
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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