Ethyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylate → 1-{4'-[4-(2-Hydroxy-ethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH2:14][CH2:15][OH:16])[c:10]([CH3:13])[n:11][o:12]2)[cH:6][cH:7]1.[CH2:17]([CH3:18])[O:19][C:20](=[O:21])[C:22]1([c:25]2[cH:26][cH:27][c:28]([B:31]3[O:32][C:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[O:39]3)[cH:29][cH:30]2)[CH2:23][CH2:24]1>>[c:2]1(-[c:28]2[cH:27][cH:26][c:25]([C:22]3([C:20]([O:19][CH2:17][CH3:18])=[O:21])[CH2:23][CH2:24]3)[cH:30][cH:29]2)[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH2:14][CH2:15][OH:16])[c:10]([CH3:13])[n:11][o:12]2)[cH:6][cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-7328af554fd3413ab881eb3bb318b50f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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