Chloroform → 1-[2-(4-Fluorophenoxy)ethyl]-4-(9-fluoro-3-propan-2-yl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine
Reaction equation
[CH:37]([Cl:38])([Cl:39])[Cl:40].[Cl:1][CH:2]1[CH2:3][c:4]2[c:5]([cH:16][c:17]([F:20])[cH:18][cH:19]2)[S:6][c:7]2[c:8]1[cH:9][c:10]([CH:13]([CH3:14])[CH3:15])[cH:11][cH:12]2.[F:21][c:22]1[cH:23][cH:24][c:25]([O:26][CH2:27][CH2:28][N:29]2[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]2)[cH:35][cH:36]1>>[CH:2]1([N:32]2[CH2:31][CH2:30][N:29]([CH2:28][CH2:27][O:26][c:25]3[cH:24][cH:23][c:22]([F:21])[cH:36][cH:35]3)[CH2:34][CH2:33]2)[CH2:3][c:4]2[c:5]([cH:16][c:17]([F:20])[cH:18][cH:19]2)[S:6][c:7]2[c:8]1[cH:9][c:10]([CH:13]([CH3:14])[CH3:15])[cH:11][cH:12]2Participants
4
Sources & evidence
- ORD record
- ord-3608bbdfb7784a25a78ec3d332c2537d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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