2-(3-fluorophenyl)benzoic Acid → [3-[(5-Bromopyrimidin-2-yl)amino]piperidin-1-yl]-[2-(3-fluorophenyl)phenyl]methanone

HRID 934990Notes

Reaction equation

HRID 934990 reaction equation
[Br:17][c:18]1[cH:19][n:20][c:21]([NH:24][CH:25]2[CH2:26][NH:27][CH2:28][CH2:29][CH2:30]2)[n:22][cH:23]1.[F:1][c:2]1[cH:3][c:4](-[c:8]2[c:9]([C:14](=[O:15])[OH:16])[cH:10][cH:11][cH:12][cH:13]2)[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[cH:3][c:4](-[c:8]2[c:9]([C:14](=[O:16])[N:27]3[CH2:26][CH:25]([NH:24][c:21]4[n:20][cH:19][c:18]([Br:17])[cH:23][n:22]4)[CH2:30][CH2:29][CH2:28]3)[cH:10][cH:11][cH:12][cH:13]2)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 27826842-(3-fluorophenyl)benzoic AcidHCID 63872105(5-Bromo-pyrimidin-2-yl)-piperidin-3-ylamine

Product 1

HCID 66639704[3-[(5-Bromopyrimidin-2-yl)amino]piperidin-1-yl]-[2-(3-fluorophenyl)phenyl]methanone

Sources & evidence

ORD record
ord-e8902f8fb5ad48c5b3995f3ec22f72d9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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