Ethanol → Tert-butyl(2-hydroxy-1-(4-hydroxyphenyl)ethyl)carbamate

HRID 935041Notes

Reaction equation

HRID 935041 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]([CH2:9][OH:10])[c:11]1[cH:12][cH:13][c:14]([O:17][CH2:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:15][cH:16]1)=[O:25].[CH3:26][CH2:27][OH:28].[Cl:29][CH2:30][Cl:31].[Pd:32]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]([CH2:9][OH:10])[c:11]1[cH:12][cH:13][c:14]([OH:17])[cH:15][cH:16]1)=[O:25]

Participants

5

Reactant 4

HCID 702EthanolHCID 6344DichloromethaneHCID 23938PalladiumHCID 22718064tert-butyl N-{1-[4-(benzyloxy)phenyl]-2-hydroxyethyl}carbamate

Product 1

HCID 67247106Tert-butyl(2-hydroxy-1-(4-hydroxyphenyl)ethyl)carbamate

Sources & evidence

ORD record
ord-5fb45c5192ea4fc59efac3ca1ccd02bc
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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