Acetic Acid → tert-Butyl 3,4-dimethylpiperazine-1-carboxylate

HRID 935061Notes

Reaction equation

HRID 935061 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH3:14])[NH:11][CH2:12][CH2:13]1.[CH3:15][OH:16].[CH3:17][C:18](=[O:19])[OH:20]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH3:14])[N:11]([CH3:15])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 887MethanolHCID 2756810tert-Butyl 3-methylpiperazine-1-carboxylate

Product 1

HCID 20785237tert-Butyl 3,4-dimethylpiperazine-1-carboxylate

Sources & evidence

ORD record
ord-833b9ce813f1419a8b4603e430d92fc4
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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