Propylenediamine → (5-Fluoro-2-trifluoromethylphenyl)-{4-[5-(5-methyl-4,5-dihydro-1H-imidazol-2-YL)pyridin-2-YL]piperazin-1-YL}methanone
Reaction equation
[F:6][c:7]1[cH:8][cH:9][c:10]([C:30]([F:31])([F:32])[F:33])[c:11]([C:12](=[O:13])[N:14]2[CH2:15][CH2:16][N:17]([c:20]3[n:21][cH:22][c:23]([C:24]([OH:25])=[O:26])[cH:27][cH:28]3)[CH2:18][CH2:19]2)[cH:29]1.[NH2:1][CH2:2][CH:3]([CH3:4])[NH2:5]>>[N:1]1=[C:24]([c:23]2[cH:22][n:21][c:20]([N:17]3[CH2:16][CH2:15][N:14]([C:12]([c:11]4[c:10]([C:30]([F:31])([F:32])[F:33])[cH:9][cH:8][c:7]([F:6])[cH:29]4)=[O:13])[CH2:19][CH2:18]3)[cH:28][cH:27]2)[NH:5][CH:3]([CH3:4])[CH2:2]1Participants
3
Sources & evidence
- ORD record
- ord-b634dd6d76f44883b1c5068847898ee3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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