Ethyl 3-{6-fluoro-7[(methylsulfanyl)methyl]-1H-indol-3-yl}-3-[4-(trifluoromethyl)phenyl]propanoate → 3-{6-Fluoro-7-[(methylsulfanyl)methyl]-1H-indol-3-yl}-3-[4-(trifluoromethyl)phenyl]propan-1-ol
Reaction equation
[Cl:31][c:32]1[cH:33][cH:34][c:35]([CH:36]([c:37]2[c:38]3[c:39]([c:40]([CH2:41][S:42][CH3:43])[c:44]([F:45])[cH:46][cH:47]3)[nH:48][cH:49]2)[CH2:50][CH2:51][OH:52])[cH:53][cH:54]1.[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([CH:14]([CH2:15][C:16](=[O:17])[O:18][CH2:19][CH3:20])[c:21]3[cH:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]3)[cH:7][nH:8][c:9]2[c:10]1[CH2:11][S:12][CH3:13]>>[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([CH:14]([CH2:15][CH2:16][OH:17])[c:21]3[cH:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]3)[cH:7][nH:8][c:9]2[c:10]1[CH2:11][S:12][CH3:13]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2c1f174ffce34891bf1ad0036039e62d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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