(Pyrimidin-5-yl)boronic acid → 4-Fluoro-1-(4-methoxyphenyl)-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine

HRID 935102Notes

Reaction equation

HRID 935102 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:8]2([c:19]3[cH:20][cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:5][cH:6][cH:7]1.[n:27]1[cH:28][n:29][cH:30][c:31]([B:33]([OH:34])[OH:35])[cH:32]1>>[c:2]1(-[c:31]2[cH:30][n:29][cH:28][n:27][cH:32]2)[cH:3][c:4]([C:8]2([c:19]3[cH:20][cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 2795193(Pyrimidin-5-yl)boronic acidHCID 585795181-(3-Bromophenyl)-4-fluoro-1-(4-methoxyphenyl)-1H-isoindol-3-amine

Product 1

HCID 462062964-Fluoro-1-(4-methoxyphenyl)-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine

Sources & evidence

ORD record
ord-8d1be64a6a78401bb36aba6d7a021487
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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