Methanol → 2-(Piperazin-1-YL)-5-(trifluoromethyl)pyrimidine
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][n:19]2)[CH2:12][CH2:13]1.[CH3:24][OH:25]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][n:19]2)[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-c2fa5f9089254f93998ef03cfe60705b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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