5,8-Difluoro-2H-chromene → 8-Bromo-6-fluoro-2H-chromene

HRID 93534Notes

Reaction equation

HRID 93534 reaction equation
[Br:13][c:14]1[c:15]([O:21][CH2:22][C:23]#[CH:24])[cH:16][cH:17][c:18]([F:20])[cH:19]1.[F:1][c:2]1[cH:3][cH:4][c:5]([F:6])[c:7]2[c:8]1[CH:9]=[CH:10][CH2:11][O:12]2>>[Br:13][c:14]1[c:15]2[c:16]([cH:17][c:18]([F:20])[cH:19]1)[CH:24]=[CH:23][CH2:22][O:21]2

Participants

3

Reactant 2

HCID 224828145,8-Difluoro-2H-chromeneHCID 224828682-Bromo-4-fluoro-1-prop-2-ynyloxybenzene

Product 1

HCID 224827988-Bromo-6-fluoro-2H-chromene

Sources & evidence

ORD record
ord-825ebc33ec554f019a15ad283a428056
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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