HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propoxybenzeneboronic acid → 2-butyl-1-isobutyl-7-(2-propoxyphenyl)-1H-imidazo[4,5-c]quinolin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propoxybenzeneboronic acid | HCID 4219796 | — |
| Reactant | 7-Bromo-2-butyl-1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine | HCID 68817944 | — |
| Product | 2-butyl-1-isobutyl-7-(2-propoxyphenyl)-1H-imidazo[4,5-c]quinolin-4-amine | HCID 21984378 | — |
Reaction Steps
7-Bromo-2-butyl-1-isobutyl-1 H-imidazo[4,5-c]quinolin-4-amine and 2-propoxybenzeneboronic acid were coupled according to the general procedure described in Part J of Example 1. The product was recrystallized from isopropanol, collected by filtration, dissolved in CH2Cl2, and then precipitated with hexanes to afford 2-butyl-1-isobutyl-7-(2-propoxyphenyl)-1H-imidazo[4,5-c]quinolin-4-amine as a white powder, m.p. 174.5–176.0° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091214B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-c102d39a905743a7a2a47a58a5ea662c |
| Source note | uspto-grants-2006_08 |