Thionyl Chloride → 2-(2,2-Difluorocyclopropyl)acetyl chloride

HRID 935476Notes

Reaction equation

HRID 935476 reaction equation
[F:1][C:2]1([F:9])[CH:3]([CH2:5][C:6](=[O:7])[OH:8])[CH2:4]1.[S:10]([Cl:11])([Cl:12])=[O:13]>>[F:1][C:2]1([F:9])[CH:3]([CH2:5][C:6](=[O:7])[Cl:12])[CH2:4]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 144585032-(2,2-Difluorocyclopropyl)acetic acid

Product 1

HCID 144585042-(2,2-Difluorocyclopropyl)acetyl chloride

Sources & evidence

ORD record
ord-308b613d2f8444d0858cd6f7a1f48370
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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