1-(But-3-yn-1-yl)piperidine → 4-[5-(4-Piperidin-1-yl-but-1-ynyl)-pyridin-3-ylmethyl]-morpholine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:8][N:9]2[CH2:10][CH2:11][O:12][CH2:13][CH2:14]2)[cH:5][n:6][cH:7]1.[CH2:15]([CH2:16][C:17]#[CH:18])[N:19]1[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]1>>[c:2]1([C:18]#[C:17][CH2:16][CH2:15][N:19]2[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]2)[cH:3][c:4]([CH2:8][N:9]2[CH2:10][CH2:11][O:12][CH2:13][CH2:14]2)[cH:5][n:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-d37d5726c7d54b0dbc7dc7f584a7b573
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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