Acetyl chloride → N-(3-{2-[4-(6-Fluoro-2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)acetamide
Reaction equation
[CH3:28][C:29]([Cl:30])=[O:31].[F:1][c:2]1[c:3]([N:13]2[CH2:14][CH2:15][N:16]([CH2:19][CH2:20][c:21]3[cH:22][c:23]([NH2:24])[cH:25][cH:26][cH:27]3)[CH2:17][CH2:18]2)[c:4]2[cH:5][cH:6][c:7]([CH3:12])[n:8][c:9]2[cH:10][cH:11]1>>[F:1][c:2]1[c:3]([N:13]2[CH2:14][CH2:15][N:16]([CH2:19][CH2:20][c:21]3[cH:22][c:23]([NH:24][C:29]([CH3:28])=[O:31])[cH:25][cH:26][cH:27]3)[CH2:17][CH2:18]2)[c:4]2[cH:5][cH:6][c:7]([CH3:12])[n:8][c:9]2[cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-72434ab559654c1abf76fef160f3c8ff
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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