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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 935719Generated: November 1, 2026

Acetonitrile → 3-Fluoro-4-(4-ethyl-3-oxopiperazin-1-yl)nitrobenzene

https://huagongshe.com/reaction/935719

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantTrifluoroacetic acidHCID 6422—
ReactantDiisopropylethylamineHCID 81531—
Reactant1,2-Difluoro-4-nitrobenzeneHCID 123053—
Reactant1-Ethylpiperazin-2-oneHCID 9877366—
Product3-Fluoro-4-(4-ethyl-3-oxopiperazin-1-yl)nitrobenzeneHCID 18783912—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-98c55f9040444ad88beb2883cfa92547
Source noteValidation data from https://doi.org/10.1039/C8SC04228D