1-(3-Fluoro-4-(5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yloxy)phenyl)-3-(2-(4-fluorophenyl)acetyl)thiourea → 4-(6-(2-(Dimethylamino)ethoxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yloxy)-3-fluorobenzenamine
Reaction equation
[F:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][n:8][n:9]3[c:10]2[c:11]([CH3:20])[c:12]([O:14][CH2:15][CH2:16][N:17]([CH3:18])[CH3:19])[cH:13]3)[cH:21][cH:22][c:23]([N+:25]([O-:26])=[O:27])[cH:24]1.[F:28][c:29]1[cH:30][c:31]([NH:32][C:33]([NH:34][C:35](=[O:36])[CH2:37][c:38]2[cH:39][cH:40][c:41]([F:42])[cH:43][cH:44]2)=[S:45])[cH:46][cH:47][c:48]1[O:49][c:50]1[c:51]2[c:52]([CH3:53])[cH:54][cH:55][n:56]2[n:57][cH:58][n:59]1>>[F:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][n:8][n:9]3[c:10]2[c:11]([CH3:20])[c:12]([O:14][CH2:15][CH2:16][N:17]([CH3:18])[CH3:19])[cH:13]3)[cH:21][cH:22][c:23]([NH2:25])[cH:24]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-10eee1abdb2849a39d7c2aab8d823afb
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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