[4-(2-Amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(4-fluoro-phenyl)-amine → 2-Chloro-N-{5-[2-(4-fluoro-phenylamino)-pyrimidin-4-yl]-4-methyl-thiazol-2-yl}-acetamide
Reaction equation
[Cl:22][CH2:23][C:24](=[O:25])[NH:26][c:27]1[s:28][c:29](-[c:30]2[cH:31][cH:32][n:33][c:34]([NH:35][c:36]3[cH:37][cH:38][cH:39][c:40]([N+:41]([O-:42])=[O:43])[cH:44]3)[n:45]2)[c:46]([CH3:47])[n:48]1.[NH2:1][c:2]1[s:3][c:4](-[c:8]2[n:9][c:10]([NH:14][c:15]3[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]3)[n:11][cH:12][cH:13]2)[c:5]([CH3:7])[n:6]1>>[NH:1]([c:2]1[s:3][c:4](-[c:8]2[n:9][c:10]([NH:14][c:15]3[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]3)[n:11][cH:12][cH:13]2)[c:5]([CH3:7])[n:6]1)[C:24]([CH2:23][Cl:22])=[O:25]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-bb1d5950524b499e82772b0b6d377e02
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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