Dichloromethane → 5-(2-chloroethyl)-1-(4'-fluorobiphenyl-2-ylmethyl)-1H-imidazole
Reaction equation
[Cl:27][CH2:28][Cl:29].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH2:14][n:15]3[cH:16][n:17][cH:18][c:19]3[CH2:20][CH2:21][OH:22])[cH:10][cH:11][cH:12][cH:13]2)[cH:6][cH:7]1.[S:23]([Cl:24])([Cl:25])=[O:26]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH2:14][n:15]3[cH:16][n:17][cH:18][c:19]3[CH2:20][CH2:21][Cl:25])[cH:10][cH:11][cH:12][cH:13]2)[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-3cfbb988702d42c9b1d876e27d14949a
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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