Carbonate Ion → 2-Bromo-6-(6-tert-butyl-1-oxo-1H-isoquinolin-2-yl)-benzaldehyde

HRID 935825Notes

Reaction equation

HRID 935825 reaction equation
[Br:16][c:17]1[c:18]([CH:19]=[O:20])[c:21]([Br:25])[cH:22][cH:23][cH:24]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]2[cH:8][cH:9][nH:10][c:11](=[O:15])[c:12]2[cH:13][cH:14]1.[C:26](=[O:27])([O-:28])[O-:29].[Cs+:30].[Cs+:31].[O:32]1[CH2:33][CH2:34][O:35][CH2:36][CH2:37]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]2[cH:8][cH:9][n:10](-[c:21]3[c:18]([CH:19]=[O:20])[c:17]([Br:16])[cH:24][cH:23][cH:22]3)[c:11](=[O:15])[c:12]2[cH:13][cH:14]1

Participants

6

Reactant 5

HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 126486412,6-DibromobenzaldehydeHCID 595638256-tert-butyl-2H-isoquinolin-1-one

Product 1

HCID 592164492-Bromo-6-(6-tert-butyl-1-oxo-1H-isoquinolin-2-yl)-benzaldehyde

Sources & evidence

ORD record
ord-9eb6d223a3c24ce4884442a8ba44f4bb
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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