1-[(5-Bromo-2-thienyl)carbonyl]pyrrolidine → [2-[(2-Methylpyrrolidin-1-yl)methyl]pyrrolidin-1-yl]-[4-[5-(pyrrolidine-1-carbonyl)thiophen-2-yl]phenyl]methanone
Reaction equation
[Br:30][c:31]1[cH:32][cH:33][c:34]([C:36](=[O:37])[N:38]2[CH2:39][CH2:40][CH2:41][CH2:42]2)[s:35]1.[CH3:1][CH:2]1[N:3]([CH2:7][CH:8]2[N:9]([C:13](=[O:14])[c:15]3[cH:16][cH:17][c:18]([B:21]4[O:22][C:23]([CH3:24])([CH3:25])[C:26]([CH3:27])([CH3:28])[O:29]4)[cH:19][cH:20]3)[CH2:10][CH2:11][CH2:12]2)[CH2:4][CH2:5][CH2:6]1>>[CH3:1][CH:2]1[N:3]([CH2:7][CH:8]2[N:9]([C:13](=[O:14])[c:15]3[cH:16][cH:17][c:18](-[c:31]4[cH:32][cH:33][c:34]([C:36](=[O:37])[N:38]5[CH2:39][CH2:40][CH2:41][CH2:42]5)[s:35]4)[cH:19][cH:20]3)[CH2:10][CH2:11][CH2:12]2)[CH2:4][CH2:5][CH2:6]1Participants
3
Sources & evidence
- ORD record
- ord-635b852136f5472e9e2e7e87dc96a816
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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