4-Ethoxyaniline → N4-(3,4-dimethoxyphenyl)-N2-(4-ethoxyphenyl)-5-fluoro-2,4-pyrimidinediamine
Reaction equation
[CH2:20]([CH3:21])[O:22][c:23]1[cH:24][cH:25][c:26]([NH2:27])[cH:28][cH:29]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]([O:17][CH3:18])[c:12]([O:15][CH3:16])[cH:13][cH:14]2)[n:7]1>>[c:2]1([NH:27][c:26]2[cH:25][cH:24][c:23]([O:22][CH2:20][CH3:21])[cH:29][cH:28]2)[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]([O:17][CH3:18])[c:12]([O:15][CH3:16])[cH:13][cH:14]2)[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-b0b8624e042040d188d2e332222c7d91
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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