Bicarbonate Ion → 4-methoxy-2-[1-(4-trifluoromethoxyphenyl)-1H-imidazol-4-yl]-benzaldehyde

HRID 935932Notes

Reaction equation

HRID 935932 reaction equation
[Br:1][c:2]1[n:3][cH:4][n:5](-[c:7]2[cH:8][cH:9][c:10]([O:13][C:14]([F:15])([F:16])[F:17])[cH:11][cH:12]2)[cH:6]1.[C:31](=[O:32])([OH:33])[O-:34].[CH2:43]1[CH2:44][CH2:45][CH2:46][CH2:47][CH2:48]1.[CH3:36][O:37][CH2:38][CH2:39][O:40][CH3:41].[CH:18](=[O:19])[c:20]1[c:21]([B:28]([OH:29])[OH:30])[cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]1.[Na+:35].[OH2:42]>>[c:2]1(-[c:21]2[c:20]([CH:18]=[O:19])[cH:25][cH:24][c:23]([O:26][CH3:27])[cH:22]2)[n:3][cH:4][n:5](-[c:7]2[cH:8][cH:9][c:10]([O:13][C:14]([F:15])([F:16])[F:17])[cH:11][cH:12]2)[cH:6]1

Participants

8

Reactant 7

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 962WaterHCID 80711,2-DimethoxyethaneHCID 8078CyclohexaneHCID 27343665-Methoxy-2-formylphenylboronic acidHCID 578244354-bromo-1-(4-(trifluoromethoxy)phenyl)-1H-imidazole

Product 1

HCID 578244154-methoxy-2-[1-(4-trifluoromethoxyphenyl)-1H-imidazol-4-yl]-benzaldehyde

Sources & evidence

ORD record
ord-9065d13140274c20a1f1192e40fa2218
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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