2-Chloro-N-methoxy-N-methylisonicotinamide → (4-Chloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(2-chloro-pyridin-4-yl)-methanone

HRID 935939Notes

Reaction equation

HRID 935939 reaction equation
[Br:1][c:2]1[cH:3][n:4]([CH:12]([CH3:13])[CH3:14])[c:5]2[n:6][cH:7][n:8][c:9]([Cl:11])[c:10]12.[Br:28][c:29]1[cH:30][c:31]([C:32]([c:33]2[c:34]3[c:35]([Cl:36])[n:37][cH:38][n:39][c:40]3[n:41]([CH:42]([CH3:43])[CH3:44])[cH:45]2)=[O:46])[cH:47][n:48][cH:49]1.[Cl:15][c:16]1[cH:17][c:18]([C:19](=[O:20])[N:21]([O:22][CH3:23])[CH3:24])[cH:25][cH:26][n:27]1>>[c:2]1([C:19]([c:18]2[cH:17][c:16]([Cl:15])[n:27][cH:26][cH:25]2)=[O:20])[cH:3][n:4]([CH:12]([CH3:13])[CH3:14])[c:5]2[n:6][cH:7][n:8][c:9]([Cl:11])[c:10]12

Participants

4

Reactant 3

HCID 185068942-Chloro-N-methoxy-N-methylisonicotinamideHCID 457894285-Bromo-4-chloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidineHCID 86603152(5-Bromo-pyridin-3-yl)-(4-chloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methanone

Product 1

HCID 86603156(4-Chloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(2-chloro-pyridin-4-yl)-methanone

Sources & evidence

ORD record
ord-d81ec4e6c36d4d5aa3f08ec6d9afdee5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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