Pyridine → (4-tert-Butoxycarbonylamino-cyclohexyl)-carbamic acid phenyl ester

HRID 936156Notes

Reaction equation

HRID 936156 reaction equation
[C:20]([CH3:21])([CH3:22])([CH3:23])[O:24][C:25]([NH:26][CH:27]1[CH2:28][CH2:29][CH:30]([NH2:33])[CH2:31][CH2:32]1)=[O:34].[Cl:17][CH2:18][Cl:19].[Cl:1][C:2](=[O:3])[O:4][c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1.[Cl:35][CH2:36][Cl:37].[cH:11]1[cH:12][cH:13][n:14][cH:15][cH:16]1>>[C:2](=[O:3])([O:4][c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[NH:33][CH:30]1[CH2:29][CH2:28][CH:27]([NH:26][C:25]([O:24][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:34])[CH2:32][CH2:31]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344Dichloromethane2×HCID 15891Phenyl chloroformateHCID 2756050Cis tert-Butyl 4-aminocyclohexylcarbamate

Product 1

HCID 67022954(4-tert-Butoxycarbonylamino-cyclohexyl)-carbamic acid phenyl ester

Sources & evidence

ORD record
ord-a9b77b76a88841a49ac30ef514b5cf9f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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