2,4-Dichloro-6-ethylpyrimidine → 2-chloro-N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-ethylpyrimidin-4-amine

HRID 936161Notes

Reaction equation

HRID 936161 reaction equation
[Cl:11][c:12]1[n:13][c:14]([NH:18][c:19]2[cH:20][c:21]([CH:24]3[CH2:25][CH2:26]3)[n:22][nH:23]2)[c:15]([Cl:16])[cH:17][n:27]1.[Cl:1][c:2]1[n:3][c:4]([CH2:9][CH3:10])[cH:5][c:6]([Cl:8])[n:7]1>>[Cl:1][c:2]1[n:3][c:4]([CH2:9][CH3:10])[cH:5][c:6]([NH:18][c:19]2[cH:20][c:21]([CH:24]3[CH2:25][CH2:26]3)[nH:22][n:23]2)[n:7]1

Participants

3

Reactant 2

HCID 2460102,4-Dichloro-6-ethylpyrimidineHCID 178478344HCID 178478344, compound

Product 1

HCID 860477102-chloro-N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-ethylpyrimidin-4-amine

Sources & evidence

ORD record
ord-190eb084cab144c09469dae4cca18859
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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