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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 936272Generated: October 25, 2026

Dichloromethane → 2-(Chloromethyl)-5-(4-(trifluoromethyl)phenyl)thiophene

https://huagongshe.com/reaction/936272

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantThionyl ChlorideHCID 24386—
Reactant2-Thiophenemethanol, 5-[4-(trifluoromethyl)phenyl]-HCID 21986352—
Product2-(Chloromethyl)-5-(4-(trifluoromethyl)phenyl)thiopheneHCID 57594979—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-f1ad49b3f3ed46e1b837864ef611c0b8
Source noteValidation data from https://doi.org/10.1039/C8SC04228D