Ethanol → 1'-[2-(4-Nitrophenyl)ethyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-ol

HRID 936280Notes

Reaction equation

HRID 936280 reaction equation
[BH4-:27].[CH3:29][CH2:30][OH:31].[Na+:28].[O:1]=[C:2]1[C:3]2([CH2:4][c:5]3[cH:6][cH:7][cH:8][cH:9][c:10]31)[CH2:11][CH2:12][N:13]([CH2:16][CH2:17][c:18]1[cH:19][cH:20][c:21]([N+:24](=[O:25])[O-:26])[cH:22][cH:23]1)[CH2:14][CH2:15]2>>[OH:1][CH:2]1[C:3]2([CH2:4][c:5]3[cH:6][cH:7][cH:8][cH:9][c:10]31)[CH2:11][CH2:12][N:13]([CH2:16][CH2:17][c:18]1[cH:19][cH:20][c:21]([N+:24](=[O:25])[O-:26])[cH:22][cH:23]1)[CH2:14][CH2:15]2

Participants

5

Reactant 4

HCID 702EthanolHCID 923Sodium ionHCID 28123BorohydrideHCID 677244561,3-dihydro-1-oxo-1'-[2-(4-nitrophenyl)-1-ethyl]-spiro[2H-indene-2,4'-piperidine]

Product 1

HCID 677246811'-[2-(4-Nitrophenyl)ethyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-ol

Sources & evidence

ORD record
ord-05bf921424ce4a188aca31530b539cac
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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