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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 93629Generated: October 30, 2026

Tetrahydrofuran → 2-tert-butyl-4-chloro-5-[4-(2-hydroxyethoxymethyl)benzyloxy]-2H-pyridazin-3-one

https://huagongshe.com/reaction/93629

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant2-t-butyl-5-{4-[2-(t-butyldimethylsilanyloxy)ethoxymethyl]benzyloxy}-4-chloro-2H-pyridazin-3-oneHCID 59678629—
Product2-tert-butyl-4-chloro-5-[4-(2-hydroxyethoxymethyl)benzyloxy]-2H-pyridazin-3-oneHCID 59678647—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-7c84bbce4d4d4aefbcd77dc0c37cae52
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)