Ethanolamine → 3-[1-[4-(2,4-Difluorophenyl)phenyl]ethyl]-6-(4-fluorophenyl)-6-[2-(2-hydroxyethylamino)ethyl]-1,3-oxazinan-2-one
Reaction equation
[CH3:1][S:2]([O:3][CH2:6][CH2:7][C:8]1([c:31]2[cH:32][cH:33][c:34]([F:37])[cH:35][cH:36]2)[CH2:9][CH2:10][N:11]([CH:15]([CH3:16])[c:17]2[cH:18][cH:19][c:20](-[c:23]3[c:24]([F:30])[cH:25][c:26]([F:29])[cH:27][cH:28]3)[cH:21][cH:22]2)[C:12](=[O:14])[O:13]1)(=[O:4])=[O:5].[CH3:42][OH:43].[NH2:38][CH2:39][CH2:40][OH:41]>>[CH2:6]([CH2:7][C:8]1([c:31]2[cH:32][cH:33][c:34]([F:37])[cH:35][cH:36]2)[CH2:9][CH2:10][N:11]([CH:15]([CH3:16])[c:17]2[cH:18][cH:19][c:20](-[c:23]3[c:24]([F:30])[cH:25][c:26]([F:29])[cH:27][cH:28]3)[cH:21][cH:22]2)[C:12](=[O:14])[O:13]1)[NH:38][CH2:39][CH2:40][OH:41]Participants
4
Sources & evidence
- ORD record
- ord-2ed7139ad0ff42d7acb1762ba45a4e1a
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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