4-Hydroxypyrrolidine → [7-(3,4-dihydro-2H-chromen-4-yloxy)-2,3-dimethylbenzimidazol-5-yl]-(3-hydroxypyrrolidin-1-yl)methanone
Reaction equation
[NH:26]1[CH2:27][CH:28]([OH:31])[CH2:29][CH2:30]1.[O:1]1[CH2:2][CH2:3][CH:4]([O:11][c:12]2[cH:13][c:14]([C:23](=[O:24])[OH:25])[cH:15][c:16]3[n:17]([CH3:22])[c:18]([CH3:21])[n:19][c:20]23)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21>>[O:1]1[CH2:2][CH2:3][CH:4]([O:11][c:12]2[cH:13][c:14]([C:23](=[O:25])[N:26]3[CH2:27][CH:28]([OH:31])[CH2:29][CH2:30]3)[cH:15][c:16]3[n:17]([CH3:22])[c:18]([CH3:21])[n:19][c:20]23)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21Participants
3
Sources & evidence
- ORD record
- ord-10842bf007c042b0a15c2ea9ff1c4f26
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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